Synthesis of 8-aroyl-9-hydroxy-7,9,11-triaryl-3-oxo(or thioxo)-2,4-diazaspiro- [5,5]undecane-1,5-diones

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Title:	Synthesis of 8-aroyl-9-hydroxy-7,9,11-triaryl-3-oxo(or thioxo)-2,4-diazaspiro- [5,5]undecane-1,5-diones
Authors:	Ahmed, S. Mosaddeq Ahmed, M. Giasuddin Ahmed, S. Asghari Sultana, Tazin Hossain, M. Mahmun Hussam, Abul
Keywords:	Spiro compounds, barbituric acid, 2-thiobarbituric acid, chalcones, Michael addition.
Issue Date:	22-Dec-2011
Publisher:	Taylor & Francis
Series/Report no.:	42(8);Page 1146-1153
Abstract:	A number of 8-aroyl-9-hydroxy-7,9,11-triaryl-3-oxo(or thioxo)-2,4-diazaspiro[5.5] undecane-1,5-diones 3a-g were synthesized from the reaction of 1,3-diaryl-2-propen-1-ones 2a-d with barbituric acid 1a and 2-thiobarbituric acid 1b in 50% aqueous ethanol under refluxing condition without using any catalyst. The structures of the compounds were confirmed by UV, IR, 1H and 13C NMR, MS and elemental analysis.
URI:	http://dspace.aiub.edu:8080/jspui/handle/123456789/178
ISSN:	1532 – 2432 (online), 0039-7911 (print)
Appears in Collections:	Publication: Journal

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